CAPRI

Novel sampling strategies and a coarse-grained score function for docking homomers, flexible heteromers, and oligosaccharides using Rosetta in CAPRI Rounds 37–45

Critical Assessment of PRediction of Interactions (CAPRI) rounds 37 through 45 introduced larger complexes, new macromolecules, and multistage assemblies. For these rounds, we used and expanded docking methods in Rosetta to model 23 target complexes. …

Modeling oblong proteins and water-mediated interfaces with RosettaDock in CAPRI rounds 28–35

The 28th–35th rounds of the Critical Assessment of PRotein Interactions (CAPRI) served as a practical benchmark for our RosettaDock protein–protein docking protocols, highlighting strengths and weaknesses of the approach. We achieved acceptable or …

Prediction of homo- and hetero-protein complexes by ab-initio and template-based docking: a CASP-CAPRI experiment

We present the results for CAPRI Round 30, the first joint CASP‐CAPRI experiment, which brought together experts from the protein structure prediction and protein–protein docking communities. The Round comprised 25 targets from amongst those …